Free monograph · 34 pages
The New IBS
From functional disorder to biological networks
IBS was long described as a "functional" disorder, defined by what tests could not find. Advances in neurogastroenterology, mucosal immunology and microbiome science are replacing that view with one of overlapping biological pathways.
This monograph walks through the emerging model, the communication between gut, brain, immune system, intestinal barrier and microbiome, and offers wording a healthcare professional can use when a patient's tests are reassuring but their symptoms are real.
Inside this monograph
- Why IBS is now classified as a disorder of gut-brain interaction
- Five emerging paradigm shifts in how IBS is understood
- The overlapping pathways: gut-brain signalling, immune activation, barrier function and the microbiome
- A useful patient explanation for "your tests are normal"
- Where microbiome science in IBS is heading
Written for healthcare professional education and free for anyone to read. It is general education, not medical advice or a treatment guideline. Speak to a healthcare professional about your own symptoms.
Prefer a shorter read? Understanding IBS covers the essentials in plain language.
